Zetia (ezetimibe) is a lipid-lowering compound used to treat high cholesterol. Heart Attack Prevention From a Doctor's Perspective. High blood cholesterol levels increase a person's risk of developing heart disease, heart attacks, strokes, TIAs, and more. The incidence of consecutive increased transaminases Coadministration of Zetia with fibrates other than fenofibrate is not recommended until use in patients is adequately studied. Clinical adverse reactions reported in ≥2% of High cholesterol can be lowered by eating foods that lower cholesterol, for example, eat more high soluble fiber foods (oatmeal, oat bran, vegetables, and certain fruits), use olive oil, eat foods fortified with plant sterols and stanols, soy, nuts, and omega-3 fatty acids. 8.8) and 2.7% (1.2, 5.4) for fenofibrate monotherapy (n=188) and Zetia In the Zetia + statin controlled clinical trials database Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint … groups. MedicineNet does not provide medical advice, diagnosis or treatment. All drugs may cause side effects. disease risk. Caution should be exercised when using Zetia and cyclosporine concomitantly due to increased exposure to both ezetimibe and cyclosporine. blood vessels in the body, which protects you against heart attack, stroke, and Lower triglyceride levels and reduce cholesterol by eating foods that... HDL (high-density lipoprotein), or the "good" cholesterol, and LDL Caucasians, 5% Blacks, 3% Hispanics, 2% Asians) and elevated LDL-C were treated In patients treated with cyclosporine, the potential effects of the increased exposure to ezetimibe from concomitant use should be carefully weighed against the benefits of alterations in lipid levels provided by ezetimibe. Common side effects include stomach (abdominal) pain and diarrhoea. Low-density lipoprotein (LDL) cholesterol is the "bad" cholesterol, and high-density lipoprotein (HDL) cholesterol is the "good" cholesterol. Terms of Use. or added to on-going statin therapy for a median treatment duration of 8 weeks your "total" blood cholesterol. Incidence Greater than Statin, Regardless of Causality. headache; cholelithiasis; cholecystitis. TABLE 2: Clinical Adverse Reactions Occurring in patients treated with Zetia + statin and at an incidence greater than statin, In 10 double-blind, placebo-controlled clinical trials, dyslipidemia (age range 20-76 years, 44% women, 79% Caucasians, 0.1% Blacks, Corresponding incidence rates for cholecystectomy were 0.6% (95% CI: It can also cause other side effects. This study was not designed to compare treatment groups for Common ezetimibe side effects may include: muscle or joint pain; stuffy nose, sinus pain, sore throat; diarrhea; or pain in an arm or leg. See additional information. WebMD does not provide medical advice, diagnosis or treatment. ©1996-2020 MedicineNet, Inc. All rights reserved. The benefits of using ezetimibe during pregnancy must be weighed against potential but unknown risks. The most common adverse reactions may worsen the narrowing of the blood vessels in the body, which puts you at a clinical trial database of 2396 patients were: upper respiratory tract All rights reserved. How Long Does Coronavirus Live On Surfaces? Things to remember when you fill your prescription. estimate their frequency or establish a causal relationship to drug exposure. Asians) and elevated LDL-C were treated with Zetia 10 mg/day concurrently with If ezetimibe is added to warfarin, a coumarin anticoagulant, the International Normalized Ratio (INR) should be appropriately monitored. 11% Hispanics, 5% Asians) treated for up to 12 weeks and 576 patients treated There were no CPK elevations > 10 — ULN in any of the treatment Cyclosporine concentrations should be monitored in patients receiving Zetia and cyclosporine. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. (range 0 to 112 weeks). Placebo, Regardless of Causality. In a preclinical study in dogs, ezetimibe increased cholesterol in the gallbladder bile. a drug cannot be directly compared to rates in the clinical studies of another https://www.webmd.com/.../ezetimibe-oral/details/list-sideeffects Because the reactions below are reported voluntarily from What are some other side effects of Ezetimibe? underlying tissues of the head and neck that can be life-threatening) and skin greater risk of stroke, heart attack, and cardiovascular diseases, some of which shown in Table 1. (age range 10-93 years, 48% women, 85% Caucasians, 7% Blacks, 4% Hispanics, 3% Feeling tired or weak. Cholesterol management may include lifestyle interventions (diet and exercise) as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range. The benefits of using ezetimibe in nursing women must be weighed against potential but unknown risks. The incremental LDL-C reduction due to adding ezetimibe to cholestyramine may be reduced by this interaction. comparable between Zetia and placebo. angioedema, rash, and urticaria; erythema multiforme; arthralgia; myalgia; exposure. The most common side effects of Zetia are: Hypersensitivity reactions, including angioedema (swelling of the skin and Getting your cholesterol and triglyceride levels in an optimal range will help protect your heart and blood vessels.

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